Since the end of 1990s, sexual assistance to people with disabilities has been the systematical subject, on an International level, of many researches and investigations. Earle (1999), Tepper (2000), Shakespeare (2000), Waxman Fiduccia (2000) pointed out taboos and silence around sexuality, as nowadays the intersection between people with disabilities and sexuality has become an emerging issue of social justice (Shuttleworth, 2007) and sexuality is an inalienable right, therefore moving from a medical to a social and cultural perspective within studies in this sector (Tepper, 2000).\nThe present study follows the same direction and, while trying to link together pedagogical knowledge and the results generated by researches within sociological, psychological and political sciences, aims at clarifying the figure of the sexual assistant, which a recent Italian bill wants to regulate, in order to promote \"healthy sexuality and psycho-physical well-being of people with disabilities\" (Parliamentary Acts, n. 1442, 9 April 2014), just like in other European countries. \nThis paper will therefore seek to develop an idea of sex education for people with disabilities as the final outcome of research that has attempted to reflect on three levels: 1. Socio-cultural; 2. Political; 3. Pedagogical. The final outcome of the research is to rethink the sexual education of persons with disabilities, presenting some lines of project guidelines in accordance with the pedagogical literature (Mannucci, 2002; Gelati, Malignano, 2003; Castelli, Mariani, 2005; Goussot, 2008; Lascioli, 2013; Castelli, Cereda, Crotti, Villa, 2013).

BACKGOUND Randomized controlled trials (RCTs) have shown that dabigatran, rivaroxaban and warfarin cause similar bleeding rates. OBJECTIVE We performed a population-based study to determine the incidence of bleeding in patients with atrial fibrillation (AF) beginning dabigatran, rivaroxaban or warfarin. Consecutive patients initiating dabigatran, rivaroxaban, or warfarin for AF during a 3 year period were identified using a computerized database. Patients who bled and required hospitalization underwent chart review. Bleeding incidences were reported as rates per 100 patient-years of treatment. RESULTS 18249 patients were included: 9564 (52.4%) received warfarin, 5976 (32.7%) dabigatran, and 2709 (14.8%) rivaroxaban. Bleeding incidences were 3.9 (95% CI, 3.6-4.4) in warfarin-treated patients, 4.2 (95% CI, 3.7-4.7) in dabigatran patients, and 4.1 (95% CI, 3.0-5.3) in rivaroxaban patients. Intracranial hemorrhage (ICH) rates were 0.71 (95% CI, 0.56-0.90) in warfarin-treated patients, 0.4 (95% CI, 0.18-0.87) in dabigatran patients, and 0.27 (95%CI, 0.10-0.80) in rivaroxaban patients. GI hemorrhage rates were 1.88 (95%CI, 1.62-2.20) in warfarin-treated patients, 2.98 (95% CI, 2.4-3.5) in dabigatran patients and 2.39 (95%CI, 1.6-3.5) in rivaroxaban patients. CONCLUSIONS Consistent with RCTs, our study shows s

The concept of ecological («sustainable») infrastructure, which can become the basis for sustainable development, was created recently (A. Tetior, 2003). Ecological infrastructure is a complex of urban, regional, global and cosmic, natural, man-made and natural-artificial objects and phenomena, which provide environmentally well-founded preservation environment of human life. It includes a system of knowledge, actions and decisions to maintain elasticity of socio-ecological system of towns and countries, ecological education, conservation of living environment, promote ecological balance, reduce the negative impacts of human activities on the natural environment, with increased resource efficiency and consuming renewable resources, with a gradual transition to negentropy technology. A more realistic creating high-quality ecological infrastructure and the living environment can replace poorly realizable concept of sustainable development.

I am the founder/ president of the Areopa Group . \nThe Areopa Group is a knowledge provider with a very strong reputation in the field of “ Intellectual Capital Accounting “ and “Applied Knowledge Management “. We are recognized for our more than 40K man-days of RD in those fields , which gave us the opportunity to become a member of several high level expert groups within the EC . See reports on the following link : http://bookshop.europa.eu/fr/final-report-from-the-expert-group-on-intellectual-property-valuation-pbKI0114460/ \nhttp://ec.europa.eu/invest-in-research/pdf/download.../2006-2977_web1.pdf\nWe have developed an IC Calculation system (IC = added value - costs) which is able to describe all the intangible assets of a company in a monetary value , based on econometrics of each asset (we have defined 77 intangible assets in total) . We also have developed a quick IC Estimation exercise that gives a first idea of the IC value of an organization . A calculation system without an IC Accounting system would not be complete , so we have developed that too . Auditors should be able to assess the IC balance sheets , so therefore we have developed an IC Auditing system based on the basic criteria of the IAS/IFRS standards . Now we are able to close the total loop of IC Calculation , IC Accounting & IC Auditing . \nIn the slipstream of our IC efforts we have also developed a model , methodologies and tools for “ capturing , storing and making re-usable the tacit and the explicit knowledge used in business processes “ . Being able to do this we can turn tacit knowledge ( liabilities ) into explicit knowledge ( assets ) . \nAll this will ultimately lead to a change in business processes of the total organization . \nWe offer this knowledge to the market based on a very unique license concept . \nSo if you want to know more about our organization or about our product lines or business model , just drop me a line and we can further explore the results of our years and years of research . \nLudo Pyis

This paper presents a method of conversion of color image of histopathological slides to grayscale as a preprocessing step for image segmentation .The method utilizes characteristics of these images to reduce the amount of information lost during the conversion. It is a global mapping scheme and the same color does not map to two different grayscale values. Color information is added to the brightness information to reduce information loss and the weights for the added color are dependent on the distribution of the pixels in a particular image. The method was tested on a large set of histopathological slide images and convincing results were obtained some of which has been published in this paper.

The purpose of this study was to verify the effectiveness of the proposed program of computer games on reducing Attention-deficit disorder in certain categories of people with special needs. The sample of the study consisted of (10) children with learning disabilities, (10) deaf children and (10) children with mild mental disabilities able to learn in primary school from the first grade to sixth grade in Jeddah city in Saudi Arabia. The students were selected by applying Diagnostic and Statistical Manual of Mental Disorders scale, fourth edition, text revision (DSM-IV-TR®) for attention deficit and hyperactivity. The researcher used electronic attention disorder scale (Alert test). The results indicated significant differences between the ranks\' scores of the experimental group of students with special needs in the certain categories before, and after the application of the program in favor of posttest measurement.