The aim of this work was to determine the differences in defence situational activity indicators between successful and less successful teams in elite men`s handball. Overall, 1848 matches of Croatian men`s Premier league were analysed. The differences in attack situational activity indicators were determined using a set of 15 variables: 1. Average number of goalkeeper`s wing shot-stopping, 2. Efficiency percentage of goalkeeper`s wing shot-stopping, 3. Average number of goalkeeper`s 7 meter shot-stopping, 4. Efficiency percentage of goalkeeper`s 7 meter shot-stopping, 5. Average number of goalkeeper`s 9 meter shot-stopping, 6. Efficiency percentage of goalkeeper`s 9 meter shot-stopping, 7. Average number of goalkeeper`s 6 meter shot-stopping, 8. Efficiency percentage of goalkeeper`s 6 meter shot-stopping, 9. Average number of goalkeeper`s half-counterattack shot-stopping, 10. Efficiency percentage of goalkeeper`s half-counterattack shot-stopping, 11. Average number of goalkeeper`s counterattack shot-stopping, 12. Efficiency percentage of goalkeeper`s counterattack shot-stopping, 13. Average number of balls won by defence players, 14. Average number of 7 meter throws executed by defence players, 15. Average number of 2-minute exclusions made by defence players. For all the examined variables of successful and less successful teams, a descriptive statistics was calculated. The statistical difference significance in the defence situational activity indicators was tested using the univariate variance analysis. The results showed a statistical significant difference between successful and less successful teams in the following variables: average number of goalkeeper`s shot-stopping from wing position, efficiency percentage of goalkeeper`s shot-stopping from wing position, average number of goalkeeper`s 7 meter shot-stopping, efficiency percentage of goalkeeper`s shot-stopping from 7 meters, average number of goalkeeper`s shot-stopping from 9 meters, efficiency percentage of goalkeeper`s shot-stopping from 9 meters, efficiency percentage of goalkeeper`s shot-stopping from half-counterattack, average number of balls won by the defence players, average number of 7 meter throws executed by defence players.