Volume 17, Issue 8 — August 2023
Department of Neuroscience, University of California, United States
Keywords: autophagy, neurodegenerative diseases, mTOR, AMPK, Beclin-1, protein aggregation, therapeutic strategies
Autophagy is a critical cellular process that maintains homeostasis by degrading damaged organelles and misfolded proteins. This review examines the molecular mechanisms underlying autophagy dysfuncti...
CRISPR Institute, Gene Editing Department, USA
Keywords: CRISPR-Cas9, gene editing, agricultural biotechnology, crop improvement, food security, sustainable agriculture, regulatory frameworks
CRISPR-Cas9 gene editing technology has revolutionized agricultural biotechnology, enabling precise modifications in crop genomes. This comprehensive review discusses current applications of CRISPR te...
Department of Microbiology, University of Warsaw, Poland; Department of Immunology, Stanford University, USA; Department of Biological Sciences, National University of Singapore, Singapore
Keywords: gut microbiome, immune system development, T-cell differentiation, microbial colonization, dietary factors, environmental exposures, infant cohort
The gut microbiome plays a crucial role in shaping immune system development during early life. This study investigates the relationship between microbial colonization patterns and immune cell maturat...
Institute for Marine and Antarctic Studies, University of Tasmania, Australia
Keywords: climate change, marine ecosystems, carbon cycling, ocean acidification, phytoplankton productivity
Ocean ecosystems are fundamental to global carbon cycling, yet climate change threatens to disrupt these critical processes. This research quantifies the impacts of rising sea temperatures and ocean a...
Department of Regenerative Medicine, University of California, USA; Cardiovascular Research Institute, Imperial College London, UK; Stem Cell Research Center, Cairo University, Egypt
Keywords: stem cell therapy, cardiovascular disease, myocardial infarction, regenerative medicine, cell engraftment, safety profiles, clinical trials
Stem cell therapy represents a promising approach for treating cardiovascular diseases, particularly myocardial infarction and heart failure. This review summarizes recent clinical trials utilizing va...