Emily Watson, Jonathan Lee, Catherine Fraser
Neuroplasticity enables the brain to reorganize and recover function following traumatic injury. This longitudinal study examines cognitive rehabilitation outcomes in 200 patients with moderate-to-severe traumatic brain injury over a two-year period. We correlate structural and functional neuroimaging changes with cognitive test performance improvements. Results indicate that intensive, task-specific rehabilitation initiated within the first three months post-injury produces the greatest gains in executive function and memory. We also identify genetic polymorphisms associated with enhanced recovery potential.