Gallstones Disease 'Cholelithiasis': Causes and Potential Treatments

Gallstones disease, or cholelithiasis, is a prevalent condition worldwide, with significant morbidity and mortality, particularly in regions like Al-Maghreb. This study investigates the unusual occurrence of gallstones in newborns in Missan city, aiming to elucidate the underlying causes and explore effective treatments. Using atomic absorption techniques, this research identified unexpected aluminum ion concentrations in gallstone samples, contradicting existing literature that typically identifies cholesterol, bile salts, phospholipids, bilirubin, calcium, and estrogen as the primary constituents. The findings suggest civilization-related dietary factors may contribute to gallstone formation. This paper proposes dietary modifications, emphasizing low-cholesterol foods with higher triacylglycerol and fatty acid content, as potential therapeutic strategies. Despite extensive research over the past century, the etiology of gallstones remains complex, necessitating further chemical analysis.