Antimicrobial Resistance Patterns in Hospital-Acquired Infections

Hospital-acquired infections caused by multidrug-resistant bacteria pose significant challenges to healthcare systems worldwide. This surveillance study analyzes antimicrobial resistance patterns among bacterial isolates from 50 hospitals across five countries over a five-year period. We document alarming increases in carbapenem-resistant Enterobacteriaceae and vancomycin-resistant enterococci. Our analysis identifies risk factors for acquisition of resistant infections and evaluates the effectiveness of antimicrobial stewardship programs. Recommendations for evidence-based infection control strategies are provided.