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Found 4 articles for "Pathogenesis"
Autophagy is a critical cellular process that maintains homeostasis by degrading damaged organelles and misfolded proteins. This review examines the molecular mechanisms underlying autophagy dysfunction in neurodegenerative diseases such as Alzheimer...
Mast cells (MCs) are a part of the innate immune system and express receptors for microbial and viral pathogens characteristic of this system. The pathological role of MCs has been demonstrated for a number of highly virulent viral infections. The ro...
A pathophysiological hallmark of hypertrophic scarring is the overactivation of fibroblasts, which results in their proliferation along with overproduction of the extracellular matrix. The Gardos channel (KCa3.1) is reported to mediate fibroblast act...
Inflammatory bowel disease (IBD) with concomitant primary sclerosing cholangitis (PSC) has emerged as a significant area of research. The epidemiology and characteristics of IBD and PSC individually have been extensively studied, enhancing our unders...