Scrophularia atropatana extract reverses TP53 gene promoter hypermethylation and decreases survivin antiapoptotic gene expression in breast cancer cells
Background: In many cases of breast cancer, the aberrant methylation of the TP53 gene leads to uncontrolled cell proliferation and apoptosis inhibition. Furthermore, expression of oncogenes controlled by the P53 protein could be altered, with survivi...