Print ISSN: 2155-3769/2689-5293 | E-ISSN: 2689-5307

Convection-Diffusion Model of Quorum Sensing in Bacteria

Sarangam Majumdar, Subhoshmita Mondal

Quorum sensing is a cell-to-cell communication mechanism mediated by chemical signals known as autoinducers. Once the concentration of these molecules surpasses a certain threshold, bacteria transition into an active or quorum state. In this study, we propose a mathematical model for quorum sensing systems and analyze this biological phenomenon through numerical simulations. We employ various computational methods, including Runge-Kutta and finite element methods, to simulate the behavior of Pseudomonas aeruginosa in batch culture. Our findings reveal the presence of a negative diffusion coefficient, which significantly influences the quorum sensing process.

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