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Found 50 articles for "India"
Understanding the complex process of protein folding is crucial for deciphering cellular functions and developing therapeutic strategies for protein-misfolding diseases. This study investigates the biophysical properties influencing the folding pathw...
Antibody engineering has significantly advanced the field of immunotherapy, providing novel approaches to enhance therapeutic efficacy against a variety of diseases. The objective of this study was to develop and optimize engineering techniques for a...
Pseudomonas aeruginosa is a prominent opportunistic pathogen responsible for severe infections, particularly in immunocompromised patients. The bacterium's ability to evade host immune responses is a significant factor in its pathogenicity. This stud...
Understanding the regulatory mechanisms of gene expression is pivotal in elucidating cellular responses to environmental stressors. This study focuses on the heat shock protein (HSP) gene expression in Drosophila melanogaster, a model organism in gen...
Climate change poses a significant threat to global biodiversity, particularly in sensitive alpine ecosystems. This study investigates how genetic diversity within plant species contributes to their ability to adapt to changing climatic conditions. O...
The increasing prevalence of environmental stresses such as drought and salinity necessitates the development of crops with enhanced stress tolerance. This study aims to investigate the role of specific genes in stress tolerance by utilizing CRISPR-C...
Protein structure prediction remains a pivotal challenge in computational biology, with significant implications for drug discovery and molecular biology. This study aims to enhance the accuracy of protein structure prediction by integrating deep lea...
The dynamic interactions between organelles are crucial for maintaining cellular homeostasis and function. This study investigates the crosstalk between mitochondria and lysosomes, two vital organelles involved in energy metabolism and cellular waste...
DNA repair is critical for maintaining genomic integrity, with poly(ADP-ribose) polymerase (PARP) playing a pivotal role in the repair of DNA double-strand breaks (DSBs). This study aims to delineate the mechanisms by which PARP facilitates DSB repai...
Understanding the dynamics of protein folding is crucial for elucidating the mechanisms underlying many biological processes and diseases. This study focuses on the role of hydrophobic interactions in the folding pathways of globular proteins. Using ...
The rapid evolution of viruses presents significant challenges to public health, primarily due to their ability to adapt quickly via mutation. This study investigates the adaptive mechanisms within RNA viruses, focusing on mutation dynamics and their...
The allosteric regulation of AMP-activated protein kinase (AMPK) plays a pivotal role in cellular energy homeostasis, making it a critical target for therapeutic intervention in metabolic disorders. Despite extensive study, the detailed structural me...
The rapid advancement in genomic technologies has generated vast amounts of data, necessitating sophisticated computational techniques for analysis. This study aims to enhance predictive modeling in genomic studies through integrative network analysi...
Morphogenesis, the biological process that causes an organism to develop its shape, is a crucial aspect of developmental biology. This study aims to elucidate the integrative mechanisms underlying epithelial folding, a fundamental morphogenetic proce...
Organelle dynamics are critical to cellular homeostasis and adaptation to stress. This study investigates the mechanisms underlying mitochondrial redistribution in response to cellular stress in mammalian cells. We aimed to elucidate the role of cyto...
The complex interplay between the MAPK and PI3K/Akt signaling pathways plays a critical role in cellular processes such as proliferation, differentiation, and survival. Despite extensive research, the precise mechanisms of crosstalk remain elusive. T...
DNA repair is a critical process that maintains genomic stability and protects against carcinogenesis. The modulation of homologous recombination (HR) pathways has shown promise in enhancing DNA repair fidelity. This study aims to elucidate the role ...
Optogenetics has revolutionized the field of neuroscience by enabling precise spatial and temporal control of neuronal activity. Despite significant advancements, challenges remain in achieving high temporal precision and minimizing photo-toxicity in...
The resilience of grassland ecosystems is critical for maintaining ecological balance and biodiversity under changing climatic conditions. This study investigates the role of adaptive thresholds in enhancing ecosystem resilience to climatic variabili...
Understanding the intricate interactions within metabolic pathways across different biological kingdoms is pivotal for advancements in biotechnology and therapeutic development. This study aims to decipher the cross-kingdom metabolic communications b...
The increasing frequency of heat waves poses significant challenges to plant growth and productivity. Understanding the mechanisms of heat stress tolerance in plants is critical for developing resilient agricultural systems. This study investigates t...
Gene therapy has emerged as a promising approach for the treatment of monogenic disorders, leveraging advances in genome editing technologies. This study aims to evaluate the efficacy and safety of CRISPR-Cas9 mediated gene therapy in correcting gene...
The intricate process of RNA splicing is crucial for the generation of mature messenger RNA (mRNA), yet the influence of small nuclear RNA (snRNA) modifications on splicing efficiency remains poorly understood. This study aims to explore the impact o...
In this article, using an Orlicz function, some new classes of zweier I-convergent triple sequence spaces of fuzzy numbers are introduced. An effort is made to study some basic algebraic and topological properties of these introduced sequence spaces....
Fifty-six curry leaf samples from farms in the Guntur district of Andhra Pradesh, India, were analyzed for 49 pesticide residues using LC-MS/MS. Recovery studies were conducted at fortification levels of 0.1, 0.05, and 0.01 mg/kg for each compound, y...
Quorum sensing is a cell-to-cell communication mechanism mediated by chemical signals known as autoinducers. Once the concentration of these molecules surpasses a certain threshold, bacteria transition into an active or quorum state. In this study, w...
The title compounds, substituted 1H-benzo[f]chromen-3-yl-2H-chromen-2-ones, were synthesized via a one-pot reaction involving 3-aryl-1-(3-coumarinyl)propen-1-ones and 2-naphthol, catalyzed by DBU and concentrated H2SO4. The resulting products were ob...
The rapid improvement in technology enables electroencephalogram (EEG) techniques to detect a diverse range of brain disorders easily. Knowledge of various signal processing techniques for the analysis of EEG signals is extremely essential. Raw EEG s...
Pyrolysis kinetics of castor seed de-oiled cake (Ricinus communis) using thermogravimetric technique was studied. The decomposition of the cake was carried out in a nitrogen atmosphere with a flow rate of 100 ml min-1 from ambient temperature to 900 ...
The liver is a vital organ responsible for numerous metabolic functions including regulation, decomposition, protein synthesis, hormone production, and detoxification. Liver failure occurs when healthy hepatocytes are damaged, leading to the formatio...
A large number of landslides present significant hazards, especially during the rainy season in the Himalayas and other hilly regions in India. The risk of landslides increases substantially with heavy rain. Once a landslide begins, it is challenging...
This paper presents a novel theorem on the approximation of almost Lipschitz functions using the Kλ-summability method in Fourier series. The Kλ-summability technique, first introduced by Karamata in 1935, has seen further development over the year...
Brake drum is one of the important components of braking system in automotive applications. Brakes of an automobile generally fail when the working stress exceeds the maximum permissible stress and excessive heating of brake drum. Heat remained in dr...
Researchers throughout the years have been searching for methods to improve the available technologies to ease the users worldwide. In medical industries, researchers have made many improvements and development in medical equipment’s to ease the me...
Big data represents a large volume of structured and unstructured data, which can be effectively managed using Hadoop, an open-source framework. This paper explores the visualization of website log files, treated as big data, using Tableau, a busines...
In this study, we explore the degree of approximation of Lipschitz functions using the (E,q) (C,1) summability method within the context of Fourier series. While previous research has extensively examined the approximation of functions in generalized...
Ultrasonic velocities, densities, and viscosities have been measured in binary liquid mixtures of quinoline with mesitylene over the entire mole fraction range of quinoline at temperatures T=(303.15, 308.15, 313.15, and 318.15)K. From the experimenta...
The quark-gluon plasma at the stage of thermodynamic equilibrium is reviewed, focusing on the quark hadron phase transition and the color superconducting phases of quark-gluon matter using phase diagrams. We analyze lattice QCD results concerning the...
Air pollution is assuming significant and even alarming dimensions, particularly in urban and industrial areas, necessitating control at the source. Industrial air pollution is generally managed by installing electrostatic precipitators, bag filters,...
The aim of the present research is to apply the optimization approach in mechanical design areas. In this paper, a recently developed algorithm called Jaya Algorithm (JA) is used for design optimization of cooling towers and pressure vessels. Jaya Al...
This paper presents a novel method for categorizing footprint images using fuzzy logic, addressing various global security challenges. Biometric footprint authentication is gaining attention due to the unique, permanent, and measurable characteristic...
The notion of N-continuous functions between generalized topological spaces has been defined. This paper relates this concept to the coN-closed generalized topology of a generalized topological space and studies the properties of coN-closed generaliz...
Non-timber forest products are a significant source of income and an integral part of development. The contribution of NTFPs to the economy is unknown and could be higher than that of timber products, still retaining significant biodiversity and ecos...
Increased interest in the clinical use of antibiotics for periodontal therapy required the development of a sensitive assay for the quantitation of levofloxacin in gingival crevicular fluid (GCF). The HPLC assay employs a C18 reversed-phase Hypersil ...
In this paper, we investigate the splitting graph of the family of bipartite graphs, focusing on paths and cycles as even sum cordial graphs. We prove that several classes of graphs, including Pm(+)Kn, (Kn[Pm) + 2K1, hW(1)n, W(2)\nn i, Bn;n, S(Bn;n),...
This paper proposes a novel approach to home cooling systems that offers significant advantages, including low power consumption, zero emissions of harmful gases, and health benefits. The core principle of the system is based on free cooling, which o...
Malignant peripheral nerve sheath tumors (MPNSTs) in the head and neck region are exceptionally rare and pose significant diagnostic and therapeutic challenges. These tumors are known for their aggressive behavior and poor prognosis. Diagnosis of MPN...
In this article, we propose and analyze a computational method for the numerical solution of general two-point boundary value problems in ordinary differential equations (ODEs). The method focuses on Helmholtz-type problems and demonstrates significa...
The advent of big data has driven a significant interest in scalable data processing frameworks, particularly in the domain of computer science. This study compares Apache Spark and MapReduce, two prominent frameworks, analyzing their performance usi...
Big data storage management is a significant challenge in Hadoop cluster environments due to the high degree of data access locality required by data-intensive applications. Traditionally, high-performance computing has relied on dedicated servers fo...