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Found 50 articles for "India"
Photosynthesis is a critical process in plants that directly affects global food production and carbon cycling. Despite its significance, the efficiency of photosynthesis in many plants remains suboptimal. This study aims to enhance the photosyntheti...
The intricate web of species interactions within temperate forest ecosystems is undergoing significant transformations due to climate change. This study aims to evaluate the effects of altered precipitation and temperature patterns on mutualistic int...
The adaptive immune response plays a crucial role in the body's defense against viral pathogens. Despite extensive research, the variability in cytokine profiles during these responses remains inadequately characterized. This study aimed to analyze t...
The hormone auxin is well-known for its pivotal role in plant development, particularly in the regulation of root architecture. This study aims to investigate the specific mechanisms through which auxin modulates lateral root development in Arabidops...
The advent of high-throughput genomic technologies has provided an unprecedented opportunity to explore the intricate relationships between genetic variations and environmental factors in the manifestation of complex traits. This study aims to elucid...
The rapid development of mRNA vaccine technology has emerged as a pivotal tool in immunology, particularly in the context of infectious disease prevention. This study aims to explore the potential of mRNA vaccine platforms in enhancing immune respons...
Biodiversity loss in fragmented landscapes poses significant challenges to conservation efforts. This study explores adaptive management strategies to enhance ecological connectivity and improve habitat quality for threatened species. Our objective w...
Climate change poses significant challenges to global agriculture, particularly in arid and semi-arid regions. To address these challenges, our study focuses on enhancing the drought resilience of wheat (Triticum aestivum). We employed an integrative...
Organelle dynamics play a crucial role in maintaining cellular homeostasis, with mitochondria and peroxisomes being central to metabolic regulation and reactive oxygen species detoxification. This study aims to elucidate the dynamic interactions betw...
Proteomics is an essential tool in biochemistry, offering insights into protein function and interaction. Our study aims to advance proteomic profiling by exploring post-translational modifications (PTMs) across varying cellular environments. We empl...
The intricate process of protein folding is pivotal to understanding cellular mechanisms and disease pathologies. In this study, we aim to elucidate the folding pathways of proteins by employing single-molecule Förster Resonance Energy Transfer (smF...
Understanding the mechanisms of cell fate determination during early embryonic development is crucial for advancing developmental biology and regenerative medicine. This study explores the intricate processes governing cell fate specification across ...
The accurate prediction of protein structures is a cornerstone of computational biology, pivotal for understanding biological functions and designing therapeutics. Despite advances, current methods face challenges in balancing prediction accuracy and...
This study investigates the intricate mechanisms of epigenetic regulation in leukocytes and its impact on cellular differentiation and immunity. Epigenetic modifications, such as DNA methylation and histone acetylation, are crucial for regulating gen...
Cell signaling via epidermal growth factor (EGF) is a critical process in regulating cellular proliferation, differentiation, and migration. The objective of this study was to elucidate the intricate crosstalk between EGF-initiated signaling pathways...
The rapid development of vaccines during the COVID-19 pandemic has highlighted the potential of mRNA-lipid nanoparticle (LNP) platforms in immunology. This study aims to explore the efficacy and safety of novel mRNA-LNP systems in eliciting immune re...
Organogenesis is a critical phase of embryonic development whereby specific organs form from a relatively undifferentiated mass of cells. Our study focuses on elucidating the genetic and molecular pathways involved in lung organogenesis using zebrafi...
The advancement of machine learning techniques offers significant potential in the field of computational biology, particularly in genomic prediction modeling. This study aims to integrate sparse genomic datasets using neural network architectures to...
The intricate interplay between interhemispheric connectivity and cognitive flexibility remains a critical area of research in neuroscience. This study aims to elucidate the dynamics of neural networks involved in cognitive flexibility, with a focus ...
Biodiversity conservation in temperate forests is increasingly challenged by habitat fragmentation. This study aims to quantify the impact of fragmentation on species richness and ecosystem functionality within these regions. Utilizing a combination ...
The process of protein folding is crucial for understanding many biological functions and dysfunctions, yet its detailed mechanisms remain elusive. This study aims to explore the kinetics of protein folding using a combination of experimental and com...
Understanding the intricacies of protein synthesis is crucial for advancing molecular biology and therapeutic development. This study investigates the role of ribosomal proteins in enhancing translation efficiency in eukaryotic cells. We employed a c...
The sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA1a) is essential for muscle function, mediating calcium transport across the sarcoplasmic reticulum membrane. Understanding the conformational states of SERCA1a during ATP binding and hydrol...
Understanding the complex process of protein folding is crucial for deciphering cellular functions and developing therapeutic strategies for protein-misfolding diseases. This study investigates the biophysical properties influencing the folding pathw...
Antibody engineering has significantly advanced the field of immunotherapy, providing novel approaches to enhance therapeutic efficacy against a variety of diseases. The objective of this study was to develop and optimize engineering techniques for a...
Pseudomonas aeruginosa is a prominent opportunistic pathogen responsible for severe infections, particularly in immunocompromised patients. The bacterium's ability to evade host immune responses is a significant factor in its pathogenicity. This stud...
Understanding the regulatory mechanisms of gene expression is pivotal in elucidating cellular responses to environmental stressors. This study focuses on the heat shock protein (HSP) gene expression in Drosophila melanogaster, a model organism in gen...
Climate change poses a significant threat to global biodiversity, particularly in sensitive alpine ecosystems. This study investigates how genetic diversity within plant species contributes to their ability to adapt to changing climatic conditions. O...
The increasing prevalence of environmental stresses such as drought and salinity necessitates the development of crops with enhanced stress tolerance. This study aims to investigate the role of specific genes in stress tolerance by utilizing CRISPR-C...
Protein structure prediction remains a pivotal challenge in computational biology, with significant implications for drug discovery and molecular biology. This study aims to enhance the accuracy of protein structure prediction by integrating deep lea...
The dynamic interactions between organelles are crucial for maintaining cellular homeostasis and function. This study investigates the crosstalk between mitochondria and lysosomes, two vital organelles involved in energy metabolism and cellular waste...
DNA repair is critical for maintaining genomic integrity, with poly(ADP-ribose) polymerase (PARP) playing a pivotal role in the repair of DNA double-strand breaks (DSBs). This study aims to delineate the mechanisms by which PARP facilitates DSB repai...
Understanding the dynamics of protein folding is crucial for elucidating the mechanisms underlying many biological processes and diseases. This study focuses on the role of hydrophobic interactions in the folding pathways of globular proteins. Using ...
The rapid evolution of viruses presents significant challenges to public health, primarily due to their ability to adapt quickly via mutation. This study investigates the adaptive mechanisms within RNA viruses, focusing on mutation dynamics and their...
The allosteric regulation of AMP-activated protein kinase (AMPK) plays a pivotal role in cellular energy homeostasis, making it a critical target for therapeutic intervention in metabolic disorders. Despite extensive study, the detailed structural me...
The rapid advancement in genomic technologies has generated vast amounts of data, necessitating sophisticated computational techniques for analysis. This study aims to enhance predictive modeling in genomic studies through integrative network analysi...
Morphogenesis, the biological process that causes an organism to develop its shape, is a crucial aspect of developmental biology. This study aims to elucidate the integrative mechanisms underlying epithelial folding, a fundamental morphogenetic proce...
Organelle dynamics are critical to cellular homeostasis and adaptation to stress. This study investigates the mechanisms underlying mitochondrial redistribution in response to cellular stress in mammalian cells. We aimed to elucidate the role of cyto...
The complex interplay between the MAPK and PI3K/Akt signaling pathways plays a critical role in cellular processes such as proliferation, differentiation, and survival. Despite extensive research, the precise mechanisms of crosstalk remain elusive. T...
DNA repair is a critical process that maintains genomic stability and protects against carcinogenesis. The modulation of homologous recombination (HR) pathways has shown promise in enhancing DNA repair fidelity. This study aims to elucidate the role ...
Optogenetics has revolutionized the field of neuroscience by enabling precise spatial and temporal control of neuronal activity. Despite significant advancements, challenges remain in achieving high temporal precision and minimizing photo-toxicity in...
The resilience of grassland ecosystems is critical for maintaining ecological balance and biodiversity under changing climatic conditions. This study investigates the role of adaptive thresholds in enhancing ecosystem resilience to climatic variabili...
Understanding the intricate interactions within metabolic pathways across different biological kingdoms is pivotal for advancements in biotechnology and therapeutic development. This study aims to decipher the cross-kingdom metabolic communications b...
The increasing frequency of heat waves poses significant challenges to plant growth and productivity. Understanding the mechanisms of heat stress tolerance in plants is critical for developing resilient agricultural systems. This study investigates t...
Gene therapy has emerged as a promising approach for the treatment of monogenic disorders, leveraging advances in genome editing technologies. This study aims to evaluate the efficacy and safety of CRISPR-Cas9 mediated gene therapy in correcting gene...
The intricate process of RNA splicing is crucial for the generation of mature messenger RNA (mRNA), yet the influence of small nuclear RNA (snRNA) modifications on splicing efficiency remains poorly understood. This study aims to explore the impact o...
In this article, using an Orlicz function, some new classes of zweier I-convergent triple sequence spaces of fuzzy numbers are introduced. An effort is made to study some basic algebraic and topological properties of these introduced sequence spaces....
Fifty-six curry leaf samples from farms in the Guntur district of Andhra Pradesh, India, were analyzed for 49 pesticide residues using LC-MS/MS. Recovery studies were conducted at fortification levels of 0.1, 0.05, and 0.01 mg/kg for each compound, y...
Quorum sensing is a cell-to-cell communication mechanism mediated by chemical signals known as autoinducers. Once the concentration of these molecules surpasses a certain threshold, bacteria transition into an active or quorum state. In this study, w...
The title compounds, substituted 1H-benzo[f]chromen-3-yl-2H-chromen-2-ones, were synthesized via a one-pot reaction involving 3-aryl-1-(3-coumarinyl)propen-1-ones and 2-naphthol, catalyzed by DBU and concentrated H2SO4. The resulting products were ob...