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Found 3 articles for "Leiden University"
The sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA1a) is essential for muscle function, mediating calcium transport across the sarcoplasmic reticulum membrane. Understanding the conformational states of SERCA1a during ATP binding and hydrol...
The rapid advancement in computational biology has opened new avenues for exploring protein-protein interaction (PPI) networks, particularly in cancer research. This study aims to elucidate the complexity of PPIs in oncogenesis and propose potential ...
DNA repair is critical for maintaining genomic integrity, with poly(ADP-ribose) polymerase (PARP) playing a pivotal role in the repair of DNA double-strand breaks (DSBs). This study aims to delineate the mechanisms by which PARP facilitates DSB repai...