Vol. 17, Issue 6
2023
ID: 4RmZw
Bei Liu, Bin Zhang, Lixia Yang, Ruiwei Guo
Objective: RNA interference (RNAi) is a widely used mechanism to knock down target gene expression. Successful application of RNAi requires efficient delivery of siRNA into cells. This study demonstrates an efficient and specific knockdown of stim1, ...
Vol. 14, Issue 1
2020
ID: MCvuc
Grazyna Adler, Iwona Zawada, Nermin Nusret Salkic, Ervin Alibegovic, Karolina Skonieczna-Zydecka, Mateusz Adler, Anna Kozlowska-Wiechowska, Violetta Sulzyc-Bielicka, Tomasz Olszowski, Beata Karakiewicz, Dariusz Bielicki
Background: The role of bacterial factors in the etiology of Crohn's disease is well-documented, yet the genetic predisposition remains a subject of extensive research. Toll-like receptor 4 (TLR4) is pivotal in recognizing bacterial lipopolysaccharid...
Vol. 10, Issue 2
2016
ID: 6iT8j
P. Aruna, A. Uma, M. Raghunath
Telomeres are critical nucleotides located at the ends of eukaryotic chromosomes, playing a vital role in maintaining genomic stability and cellular function. These structures prevent the degradation of DNA and are crucial in determining the fate of ...