Vol. 20, Issue 2
2026
ID: 3NXaB
Stefan J. Müller, Mei-Ling Hu, Rajiv N. Patel
Protein structure prediction remains a pivotal challenge in computational biology, with significant implications for drug discovery and molecular biology. This study aims to enhance the accuracy of protein structure prediction by integrating deep lea...
Vol. 20, Issue 2
2026
ID: fDDKh
Helena K. Fischer, Sunil Bhattacharya, Zhao Ming-Wei
The dynamic interactions between organelles are crucial for maintaining cellular homeostasis and function. This study investigates the crosstalk between mitochondria and lysosomes, two vital organelles involved in energy metabolism and cellular waste...
Vol. 19, Issue 12
2025
ID: 7YU6p
Astrid M. Fischer, Hiroshi Sugimoto, Priya N. Kumar
Organelle dynamics are critical to cellular homeostasis and adaptation to stress. This study investigates the mechanisms underlying mitochondrial redistribution in response to cellular stress in mammalian cells. We aimed to elucidate the role of cyto...
Vol. 19, Issue 10
2025
ID: ZuSvs
Lu Wei-Ming, Dieter H. Schneider, Priya Venkataraman
Gene therapy has emerged as a promising approach for the treatment of monogenic disorders, leveraging advances in genome editing technologies. This study aims to evaluate the efficacy and safety of CRISPR-Cas9 mediated gene therapy in correcting gene...
Vol. 19, Issue 10
2025
ID: F8Xvk
Hannes F. Müller, Aditi R. Nair, Zhang Min-Jie
The intricate process of RNA splicing is crucial for the generation of mature messenger RNA (mRNA), yet the influence of small nuclear RNA (snRNA) modifications on splicing efficiency remains poorly understood. This study aims to explore the impact o...