Vol. 19, Issue 12
2025
ID: 7YU6p
Astrid M. Fischer, Hiroshi Sugimoto, Priya N. Kumar
Organelle dynamics are critical to cellular homeostasis and adaptation to stress. This study investigates the mechanisms underlying mitochondrial redistribution in response to cellular stress in mammalian cells. We aimed to elucidate the role of cyto...
Vol. 19, Issue 10
2025
ID: ZuSvs
Lu Wei-Ming, Dieter H. Schneider, Priya Venkataraman
Gene therapy has emerged as a promising approach for the treatment of monogenic disorders, leveraging advances in genome editing technologies. This study aims to evaluate the efficacy and safety of CRISPR-Cas9 mediated gene therapy in correcting gene...
Vol. 19, Issue 10
2025
ID: F8Xvk
Hannes F. Müller, Aditi R. Nair, Zhang Min-Jie
The intricate process of RNA splicing is crucial for the generation of mature messenger RNA (mRNA), yet the influence of small nuclear RNA (snRNA) modifications on splicing efficiency remains poorly understood. This study aims to explore the impact o...